Multilineage differentiation of instruction

 

 

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* Summary Long non-coding RNAs (lncRNAs) show patterns of tissue- and cell-type-specific expression that are very similar to those of protein coding genes and consequently have the potential to control stem and progenitor cell fate decisions along a differentiation trajectory. To understand the roles that One of these, Spehd, showed defective multilineage differentiation, and its silencing yielded common myeloid progenitors that are decient in their oxida-tive Spehd emerged from this approach as an lncRNA required for stem cell differentiation. HSCs with reduced levels of Spehd show a decreased Many translated example sentences containing "multilineage differentiation" - Russian-English dictionary and search engine for Russian translations. Look up in Linguee. Suggest as a translation of "multilineage differentiation". Copy. Mesenchymal stromal cells (MSCs) are a heterogeneous population of cells that possess multilineage differentiation potential and extensive immunomodulatory Further investigations revealed that the significant enhancement of adipogenic differentiation in NOS2-/- MSCs was due to overactivation of Multilineage Differentiation and Characterization of the Human Fetal Osteoblastic 1.19 Cell Line: A Possible In Vitro Model of Human Mesenchymal Progenitors. HFOB not only have the ability to undergo multilineage differentiation but portray several important aspects of human bone marrow Spinal cord injury induces the proliferation of putative stem cells derived from the ependyma that migrate towards the site of injury. Ependymal cell progeny differentiate and give rise to astrocytes as well as myelinating oligodendrocytes. Multilineage differentiation potential was assessed using the StemPro Adipogenesis, Osteogenesis or Chondrogenesis Kit (Life Technologies) as per the instructions of the manufacturer. After differentiation, adipogenesis induction was assessed by Sudan Black staining. Furthermore, cells differentiated into different cell types (hepatocellular cells, osteogenic cells, adipogenic cells and chondrogenic cells) under special induced medium, and the marker genes of induced cells were identified with Immunofluorescence staining and RT-PCR. MSC Differentiation: The Caveat of In Vitro Studies. MSCs have been studied in several species, especially humans (Castro-Malaspina et al., 1980; Haynesworth Differentiation Potency of Culture-Expanded MSCs. One of the criteria to dene MSCs is their ability to dif-ferentiate into the osteogenic Intravenously injected multilineage-differentiating stress-enduring (Muse) cells, endogenous Multilineage-differentiating stress-enduring (Muse) cells were first reported by Kuroda and To investigate the in vitro differentiation capacity of Muse cells in the AA microenvironment, co-culture However, compared with BMSCs, tissue-derived cells showed less capacity for multilineage differentiation when the level of differentiation was Taken together, these results indicate that cells derived from tissue explant cultures reserved certain degree of differentiation properties of MSCs . DMSCs differentiated into derivatives of all germ layers. Clonally expanded DMSCs differentiated into all embryonic layers, including pulmonary cells. DMSCs showed higher life span than placental cells from fetal origin and proliferated without genomic instability. DMSCs differentiated into derivatives of all germ layers. Clonally expanded DMSCs differentiated into all embryonic layers, including pulmonary cells. DMSCs showed higher life span than placental cells from fetal origin and proliferated without genomic instability. Establishing the differentiation of MSCs into desired lineage-committed progenitors in the presence of a certain plant extract can open a new horizon for According to ISCT criteria, MSCs must be able to differentiate into multilineage cells including osteoblasts, adipocytes, and chondroblasts but it

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